Epstein-Barr virus latency: current and future perspectives
نویسندگان
چکیده
منابع مشابه
Epstein-Barr virus at 50—future perspectives
The special November and December issues of the Chinese Journal of Cancer celebrate the 50th anniversary of the discovery of Epstein-Barr virus (EBV) with a series of reviews covering the association of the virus with various cancers, with special emphasis on the role of EBV in the pathogenesis of nasopharyngeal cancer (NPC). The restricted geographic prevalence of NPC along with the tumor's co...
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Epstein-Barr virus (EBV) infects 95% of the adult population and is the cause of infectious mononucleosis. It is also associated with 1% of cancers worldwide, such as nasopharyngeal carcinoma, Hodgkin's lymphoma and Burkitt's lymphoma. Human and cancer genetic studies are now major forces determining gene variants associated with many cancers, including nasopharyngeal carcinoma and Hodgkin's ly...
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Background: Breast cancer is the most common malignancy in females worldwide. Several etiological factors including environmental factors have been recognized for breast cancer. Epstein Barr virus as a viral etiological factor has been proposed. So far, several studies have investigated the relationship between development of breast cancer and Epstein Barr virus, but few have been done in Iran....
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By cloning the HR-1 Burkitt lymphoma line, we previously uncovered two distinct biological variants of nontransforming Epstein-Barr virus (EBV). The most commonly cloned variant has a low rate of spontaneous viral synthesis and is unable to induce early antigen in Raji cells (EAI-). A rare variant spontaneously releases virus which is capable of inducing early antigen in Raji cells (EAI+). Sinc...
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ژورنال
عنوان ژورنال: Current Opinion in Virology
سال: 2015
ISSN: 1879-6257
DOI: 10.1016/j.coviro.2015.09.007